Pattern of pyogenic pathogens and their antimicrobial sensitivity in pus isolates at rural tertiary care hospital in North India

Rachna; Jogender; Mohammad Suhaib; Prasanna Gupta

Volume : VIII, Issue : II, February - 2019

Pattern of pyogenic pathogens and their antimicrobial sensitivity in pus isolates at rural tertiary care hospital in North India

Rachna, Jogender, Mohammad Suhaib, Prasanna Gupta

Abstract :

Introduction–The skin and soft infections (SSTIs) is one of the most common complications after trauma, burn, and surgical procedures resulting pus, which is a collection of dead WBCs, cellular deis, and necrotic tissues. The emergence of resistance necessitates periodic studies to determine their antibiogram. The objective of the current study is to characterize the pyogenic bacteria and to determine their antibiotic susceptibilities. Materials and Methods– Pus samples from National institute of medical science (NIMS) Hospital was collected and processed as per CLSI guidelines. Results–Analysis of 216 pus samples showed 73.81% culture positivity (M: F=1:0.45). E.coli (33.87%) was the most common organism followed by Staphylococcus aureus(29.03%).The most sensitive drug in Gram negative bacteria were susceptible to Imipenem(96.60%) Teglicyclin(95.45%). The most sensitive drug among Gram positive cocci was Linezolid(100%), Vancomycin(100%), Teicoplanin (92.60%). The most sensitive drug in Pseudomonas spp. was Imipenem(90%), Piperacillin–Tazobactum(90%), Aztreonam(90%). The most sensitive drug in CONS was Vancomycin(100%),Linezolid(100%), Tetracycline(85.71%), Doxycycline(78.57%). Conclusion–Rapid emergence of multidrug–resistant bacteria poses a serious threat to public health globally due to the limited treatment options however the changing trends of antimicrobial susceptibility in bacterial isolates from pus can serve as a vital tool for clinicians to start empirical treatment of patients at the earliest.