Pattern of uveitis in patients with various types of systemic tuberculosis

Prof. Radha Annamalai; Dr. Nitin Ramanujam; Prof. Dr. M. Muthayya

Volume : VII, Issue : VI, June - 2018

Pattern of uveitis in patients with various types of systemic tuberculosis

Prof. Radha Annamalai, Dr. Nitin Ramanujam, Prof. Dr. M. Muthayya

Abstract :

Introduction: Tubercular uveitis is a frequent cause of visual morbidity. Ocular inflammation can have rapid disseminationand result in anterior, intermediate, posterior or panuveitis.

Materials and methods: This is a prospective study on 125 patients over three years. Patients with tuberculosiswere evaluated for uveitis at a Uveitis clinic at Sri Ramachandra University, Chennai. Angiography, complete blood count, X–ray, polymerase chain reaction and biopsywereperformed on blood, aqueous and vitreous. Treatment was with ATT.

Results: Among 125 patients, Uveitis was present in 12%and posterior type was the most common with p< 0.05. Manifestation was earliest in miliary and pulmonary tuberculosis. Active disease had more severe uveitis than latent TB.Response to ATT was seen in 93%.

Conclusion – Uveitis due to TB can occur in pulmonary and extrapulmonary TB. Ophthalmic evaluation of both latentand active TB can prevent visual loss.