PERFORATION PERITONITIS: A RARE INITIAL PRESENTATION OF GASTRO INTESTINAL STROMAL TUMORS GIST‘s

Dr. Vijay haralgat seetharamaiah; Dr.Ranganatha .d.n; Dr. Umrao singh; Dr. Mahesh joshi

Volume : V, Issue : IV, April - 2016

PERFORATION PERITONITIS: A RARE INITIAL PRESENTATION OF GASTRO INTESTINAL STROMAL TUMORS GIST‘s

Dr. Vijay Haralgat Seetharamaiah, Dr. Ranganatha . D. N, Dr. Umrao Singh, Dr. Mahesh Joshi

Abstract :

GIST�s are the commonest mesenchymal tumors of gastrointestinal (G.I) system with incidence rate of 10–20 per million people [1]. Stomach is the most common organ involved followed by small intestine [2,3]. GIST�s can be benign or malignant in nature. Only 70% cases are symptomatic, rest 30% are asymptomatic. Gastro intestinal bleeding in the form of melaena, hematemesis or anemia is the most frequent presentations. [3] Other manifestations of GIST�s are mass effect, intestinal obstruction, pain abdomen, symptoms of metastasis. [4] GIST�s originates from pacemaker cells known as interstial cells of cajal. [5] Perforation peritonitis is a rare presentation of GIST�s. In past, diagnosis of GIST�s been difficult, but at present due to development of methods to identify C–kit oncogene, diagnosis has become ease [6]. Here we are reporting a case of jejunal GIST initially presenting as perforation peritonitis in 26 year old male.