Volume : II, Issue : II, February - 2013

Photodynamic Therapy: An Overview

Dr. Rizwan M Sanadi

Abstract :

Photodynamic therapy (PDT), also known as photoradiation therapy, phototherapy, or photochemotherapy, involves the use of a photoactive dye (photosensitizer) that is activated by exposure to light of a specific wavelength in the presence of oxygen. The transfer of energy from the activated photosensitizer to available oxygen results in the formation of toxic oxygen species, such as singlet oxygen and free radicals. These very reactive chemical species can damage proteins, lipids, nucleic acids, and other cellular components. PDT has shown potential in the treatment of oral leukoplakia, oral lichen planus, and head and neck cancer. PDT also represents a novel therapeutic approach in the management of oral biofilms. Photodynamic killing of periodontopathogenic bacteria may be an alternative to the systemic application of antibacterial drugs used in the treatment of periodontal diseases.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr. Rizwan M Sanadi Photodynamic Therapy: An Overview International Journal of Scientific Research, Vol.II, Issue.II February 2013

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