Volume : VIII, Issue : IV, April - 2019

PLACENTAL PATHOLOGY IN INTRAUTERINE GROWTH RESTRICTION AND ITS RELATION TO PERINATAL OUTCOME

Rekha J, Krishnaveni V

Abstract :

AIMS AND OBJECTIVES:1)Histopathological examination of placenta of IUGR babies.2)Determine the frequency and cumulative number of placental abnormalities.3)To correlate the data with perinatal outcome in terms of fetal weight, apgar scores and perinatal mortality. METHOD OF STUDY: Analytical study for a duration of six months. Analysis of the placentas of IUGR babies both microscopically and macroscopically and the results are correlated with the perinatal outcome. RESULTS AND ANALYSIS:100 placentas of mothers who delivered IUGR babies were analysed.Majority of women were primigravida and in the age group of 21–30 years.45 cases were of unexplained etiology.66 cases had abnormal Doppler flow and 34 cases had gross macroscopic abnormalities of placenta.Histopathological examination revealed multiple placental abnormalities with >3 lesions in 83 cases. Weight of placenta and weight of baby was significantly reduced with 3 or more lesions. The incidence of neonatal complications were significantly increased with multiple lesions.Apgar score at birth was also significantly reduced with multiple lesions. All cases (19 out of 100 cases) of perinatal mortality were in the group with multiple placental lesions. CONCLUSION: Increased frequency of placental lesions and increased number of lesions were significantly associated with IUGR.Increased number of placental lesions were commonly observed in cases with abnormal Doppler waveforms. Multiple placental lesions were associated with low birth weight, low placental weight, increased frequency of neonatal complications and increased perinatal mortality.:

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

PLACENTAL PATHOLOGY IN INTRAUTERINE GROWTH RESTRICTION AND ITS RELATION TO PERINATAL OUTCOME, Rekha J, Krishnaveni V INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-4 | April-2019

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