Volume : IV, Issue : II, February - 2015

PREDICTIVE MARKERS FOR SURVIVAL OF BREAST CANCER (THE ANJELINA JOLIE SYNROME)

Dr. Shilpisahu, Dr. Vibha Gajera, Dr. Reeta Dhar

Abstract :

Breast cancer is the most common leading female cancer in the world .There are various prognostic markers in survival of east cancer which has prognostic & therapeutic applications. About 75% of all east cancers are “ER positive” & 65% are “PR positive” likely to respond to endocrine therapy. Some east cancer(10% to 17%)are known as “triple negative” because they lack estrogen and progesterone receptors and do not overexpress the HER2 protein. Evaluation of ER, PR and HER-2/neu expression by immunohistochemistry (IHC) is routinely performed in east carcinomas.Over expression of HER-2 is prognostic maker of tumor aggressiveness, responsiveness to adjuvant therapy & poor survival in east cancer.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.ShilpiSahu, Dr.Vibha Gajera, Dr. Reeta Dhar PREDICTIVE MARKERS FOR SURVIVAL OF BREAST CANCER (THE ANJELINA JOLIE SYNROME) International Journal of Scientific Research, Vol : 4, Issue : 2 February 2015

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