PREVALENCE AND ANTIBIOGRAM OF HOSPITAL ACQUIRED MRSA AND COMMUNITY ACQUIRED MRSA WITH SPECIAL REFERENCE TO INDUCIBLE CLINDAMYCIN RESISTANCE IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL: A CROSS SECTIONAL STUDY

Mr. Surendra Prashad Chauhan; Dr. Khyati Jain; Md. Mustafa Sofiur Rahman; Dr. Smita Bawankar

Volume : VII, Issue : VI, June - 2018

PREVALENCE AND ANTIBIOGRAM OF HOSPITAL ACQUIRED MRSA AND COMMUNITY ACQUIRED MRSA WITH SPECIAL REFERENCE TO INDUCIBLE CLINDAMYCIN RESISTANCE IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL: A CROSS SECTIONAL STUDY

Mr. Surendra Prashad Chauhan, Dr. Khyati Jain, Md. Mustafa Sofiur Rahman, Dr. Smita Bawankar

Abstract :

BACKGROUND: The multitudes of health ailments methicillin resistant Staphylococcus aureus (MRSA) inflict on human�s remains a major issue worldwide. Knowing epidemiology of hospital acquired and community acquired MRSA along with rate of inducible Clindamycin resistance is important for deciding empirical treatment in case of MRSA infection.

AIM: To know prevalence and antibiogram of hospital acquired MRSA (HA–MRSA) and community acquired MRSA (CA–MRSA) and to determine rate of inducible Clindamycin resistance among MRSA isolates.

METHODS: A cross sectional study done in Department of Microbiology, Shri Shankaracharya Medical College, Bhilai; from 2017 to 2018. Processing of sample was done by standard protocol and antibiotic sensitivity test was done according to CSLI guidelines. MRSA was detected by using cefoxitin disc and inducible Clindamycin resistance was detected by using D–test. HA–MRSA and CA–MRSA were differentiated by asking history of patient.

RESULTS: Prevalence of MRSA in our study was 35.5% among S.aureus. Among MRSA prevalence of HA–MRSA was 64.7%. D–test positivity in MRSA was 22.53%. HA–MRSA isolates were more antibiotic resistant than CA–MRSA.

CONCLUSION: Formulation of treatment protocol should be done by periodic surveillance of MRSA in hospital because of their changing pattern of antimicrobial resistance. D–test should be routinely done for deciding treatment.