Volume : V, Issue : II, February - 2016

PREVALENCE AND RISK FACTORS OF OSTEOARTHRITIS IN MADINAH, SAUDI ARABIA, 2015.

Wejdan Munawir Alamri, Asim Jezaa Alamri, Linah Zaal Aljohani, Amal Faisal Almohammdi, Mohammed Sabri Saber, Rayan Jamal

Abstract :

 Objective. According to experts of International Association on the Study of Pain, 12% of patients older than 40 years complained of pain in the joints, 50% of older people experience difficulty walking and climbing stairs, more than 15% are expressly limited mobility, and after 75 years this figure rises to 30%. The reason – is progressive degenerative lesions of joints cartilage structure or deforming osteoarthrosis (OA). Risk factors of OA can be divided into genetic ( female sex, mutation of collagen II gene (COL2A1), inherited disorders of collagen II, hereditary pathology of bones and joints, ethnicity), non–genetic (age over 45, overweight, postmenopause, deficiency of vitamin D, inflammatory diseases of the joints, endocrine diseases, metabolic disorders, hypertension, hyperuricemia, aseptic necrosis of bones, osteoporosis) and factors of environment (surgery, joint injuries, occupational stress, over–employment sports). The aim of current research was to determine the prevalence and to identify the risk factors of knee osteoarthrosis in Medina, Saudi Arabia. Methodology. The study was conducted in two stages: 1) Evaluation of the prevalence of knee OA in the King Fahd Hospital (n = 6270) – analytic retrospective study for the period July–November 2015; 2) Evaluation of clinical and anamnestic characteristics of patients with knee OA and identifying of risk factors for knee OA (the main group – with knee OA (n=220), the compare – without knee OAs (n=220)) –"case–control" study for the period July–November 2015. Socio–demographic and clinical variables was gathered by calling the patients and the filled questionnaires during the call and also by meeting the patients in the clinics. The data were entered into a unified computer database. Statistical analysis was performed using the application package IBM SPSS 20 (SPSS Inc., Chicago, USA). Results of the study showed, that the prevalence of knee OA in the King Fahd Hospital (Medina, Saudi Arabia) for the period July–November 2015 amounted to 24.88%. The study found the most important risk factors for knee OA: age more than 50 years, smoking, diabetes mellitus, trauma in past history, the number of pregnancies in anamnesis more than 10, menopause and absence of hormonal replacement therapy (HRT). Conclusions. Current research identified the main risk factors for knee OA in King Fahd Hospital in Medina, Saudi Arabia. Some of them are controllable, and some of them cannot be changed. The present study supports the need for further epidemiological and intervention studies in order to find new approaches to prevention of development and progression of knee OA.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Wejdan Munawir Alamri, Asim Jezaa Alamri, Linah Zaal Aljohani, Amal Faisal Almohammdi, Mohammed Sabri Saber, Rayan Jamal Prevalence and Risk Factors of Osteoarthritis in Madinah, Saudi Arabia, 2015 . International Journal of Scientific Research, Vol : 5, Issue : 2 February 2016

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