Prevalence of Helicobacter pylori infection in patients presenting with dyspeptic symptoms in and around Kanchipuram

Syed Shafiq; Dr. (Mrs.) B. Ramathilagam

Volume : VIII, Issue : II, February - 2019

Prevalence of Helicobacter pylori infection in patients presenting with dyspeptic symptoms in and around Kanchipuram

Syed Shafiq, Dr. Mrs. B. Ramathilagam

Abstract :

AIMS AND OBJECTIVES: 1. To study the prevalence of Helicobacter pylori infection in patients undergoing endoscopy with biopsy for dyspeptic symptoms in a tertiary care teaching hospital. 2. To study the correlation between endoscopic and rapid urease testing (RUT)/histopathologic findings in these patients.

MATERIALS AND METHOD: A prospective study with 130 patients presenting to the Medical Gastroenterology OPD at Meenakshi Medical College Hospital and Research Institute, Kanchipuram, with complaints of dyspepsia. The study extended over a 2–year period, from August 2012 to July 2014. Patients were selected based on the inclusion and exclusion criteria.

RESULTS AND CONCLUSIONS: A total of 130 patients were enrolled in this study, the majority of whom were males (n=78), and who presented with dyspeptic symptoms underwent OGD with gastric biopsies for RUT as well as histopathology for dectection of H.pylori. The endoscopic findings of each patient were correlated with RUT and/or histology. Out of the 130 patients, 101 (77.69%) tested positive for H.pylori (either RUT or histology for H.pylori or both was positive). Histology of the gastric biopsy specimen was positive for H. pylori in 85 patients and 82 of them were positive for RUT. In our study, RUT was as sensitive as histology for detection of H.pylori infection.