Prevalence of Mycobacterium tuberculosis strains and rifampicin monoresistance in newly diagnosed cases from East Maharashtra region.

Virendra Kolhe; Shital Dhoble

Volume : VI, Issue : VIII, August - 2017

Prevalence of Mycobacterium tuberculosis strains and rifampicin monoresistance in newly diagnosed cases from East Maharashtra region.

Virendra Kolhe, Shital Dhoble

Abstract :

Introduction: Tuberculosis (TB) is one of the major causes of morbidity and mortality worldwide. Also MDR–TB and HIV–TB co–infection are major hurdles in achieving aim and objective of national tuberculosis programme.

Material and method: this retrospective study included 1364 suspected patients from April 2016 to March 2017 from registered RNTCP patients. The samples were subjected to Xpert MTB/RIF Assay. Data was tabulated and analyzed using spss 16.

Results: out of total 1364 suspected TB cases, 155 (11.36%) were detected with mycobacterium tuberculosis, whereas 1209 (88.64%) were negative for tuberculosis. Out of 155 tuberculosis patients, 64 (41.29%) were HIV positive, 59 (38.06%) had extra–pulmonary TB, 8 (5.16%) were children and 24 (15.48%) were other clinically tested. 64 (7.56%) patients have HIV–TB co–infection. Out of total 155 confirmed TB cases, 7 (4.516%) patients had rifampicin resistance

Conclusion: Prevalence of mycobacterium tuberculosis and rifampicin resistance is found to be high suggesting need of awareness about the condition and its spread.