Prevalence of nonalcoholic fatty liver disease in overweight adults of rural area and its clinical and biochemical correlation

Dr Prerna Panjeta; Dr Vikram Kala; Pareena Malik; Ashutosh Kumar; Dr Tek Chand Yadav; Dr Navtej Singh

Volume : IX, Issue : II, February - 2020

Prevalence of nonalcoholic fatty liver disease in overweight adults of rural area and its clinical and biochemical correlation

Dr Prerna Panjeta, Dr Vikram Kala, Pareena Malik, Ashutosh Kumar, Dr Tek Chand Yadav, Dr Navtej Singh

Abstract :

Nonalcoholic fatty liver disease (NAFLD) is defined as presence of fat in the liver either on imaging or on liver histology after exclusion of secondary causes of fat accumulation, i.e., significant alcohol consumption, certain medications, and other medical conditions. It ultimately progresses to hepatic fiosis, cirrhosis and liver failure. NAFLD is one of the most common chronic liver diseases worldwide and is a significant cause of morbidity in all age groups. Prevalence of NAFLD is estimated to be around 9–32% in the general population of India with a higher incidence among the obese. In this study total 60 overweight patients selected from general medicine outdoor and indoor patient. Correlation of NAFLD in overweight adults with Clinical and biochemical parameters like Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Fasting blood glucose, Triglycerides, Total cholesterol, High–density lipoprotein was analyzed. NAFLD show positive significant correlation with BMI (P=0.001), WAIST SIZE (P=.004), HIP LEVEL SIZE (.005), and show no significance with other biochemical parameters.