PREVALENCE OF SUBCLINICAL HYPOTHYROIDISM IN GALL BLADDER STONE AND CBD STONE DISEASE PATIENTS - A THREE YEAR STUDY

Dr. Hanuman Ram Khoja; Dr. Pankaj Somani; Dr. Saumya Somani; Dr. Ravi Hisariya; Dr. Anil khyalia; Dr. Pramod Chandolia

Volume : VII, Issue : V, May - 2018

PREVALENCE OF SUBCLINICAL HYPOTHYROIDISM IN GALL BLADDER STONE AND CBD STONE DISEASE PATIENTS - A THREE YEAR STUDY

Dr. Hanuman Ram Khoja, Dr. Pankaj Somani, Dr. Saumya Somani, Dr. Ravi Hisariya, Dr. Anil Khyalia, Dr. Pramod Chandolia

Abstract :

– For decades there has been discussion whether thyroid disorders could cause gall stone diseases. . A cross sectional study was done in Dept of General Surgery, S.M.S. Medical college, Jaipur from july 2014 to june 2017 to know the prevalence of subclinical hypothyroidism in patients with biliary stone (gall stone +/– CBD stone) disease in a tertiary care centre. . During this period total of 205 patients with gall stone disease (study group) and 202 (control group) were studied to see the relation between hypothyroidism and biliary stones disease. For every patient with diagnosed gallstone, full history and clinical examination was taken and laboratory blood test for T3, T4 and TSH. A total of 205 cases were included in the study groupout of which 168 (82%) were females and 37(18%) were males , 170 (83%) had only gall bladder stones whereas 35 (17%) had both gall bladder and CBD stones. . The maximum no. of cases belonged to the age groups between 21–50 yrs. 54(26%) patients of gall stone had subclinical hypothyroidism than 18(9%) of non gall stone patients.

Out of these 54 patients with Sub clinical hypothyroidism 47 were female where as remaining 7 were male. Peak age was less than 40 years. In this study, the higher proportion of hypothyroidism in women with cholelithiasis compared to men was mainly due the earlier symptomatology of gallstone disease in women as well as the higher incidence of thyroid disease in women in general. This leads to an earlier detection and treatment of hypothyroidism in women. Female patients with Gallstones should be checked for serum TSH, T3 and T4 because of high incidence of hypothyroidism among group.