Volume : VII, Issue : IX, September - 2018

Prophylactic use of Tranexamic acid in off pump coronary artery bypass surgery: Retrospective analysis

Dr Rajendra Umbarkar, Dr Pushkar Desai

Abstract :

BACKGROUND:

Off pump coronary artery bypass surgery is often associated with significant blood loss and allogenic blood transfusion and use of antifiinolytic agent like tranexamic acid has a potential in mitigating these side effects.

METHODS:

Forty two patients who underwent elective OPCAB surgery were analyzed retrospectively. All patients after standard narcotic induction received bolus intravenous dose of tranexamic acid 10 mg/kg before skin incision. Data was analyzed for 24–hour postoperative chest tube drainage, blood products transfusion, morbidity and mortality.

RESULTS: Mean intraoperative blood loss was 450 + 91.73 ml and 24 hours drainage was 450 + 91.73 ml. PRBC transfusion was required in 9.5%    patients. There were no thrombotic complications, stroke, renal failure and mortality.

CONCLUSION: Prophylactic tranexamic acid is a safe strategy during OPCAB to reduce peri–operative blood loss.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Rajendra Umbarkar, Dr Pushkar Desai, Prophylactic use of Tranexamic acid in off pump coronary artery bypass surgery: Retrospective analysis, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-9 | September-2018

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