Volume : IX, Issue : VI, June - 2020

PULMONARY HYPERTENSION IN PULMONARY TUBERCULOSIS PATIENTS

Dr. Rajat Jain, Dr. Zaki Siddiqui, Dr. Sunit Kumar Verma

Abstract :

Introduction: Right heart failure is not an unusual finding in patients of Pulmonary TB, especially in a high burden country like India. These patients usually have a grave prognosis. It is essential to screen patients of pulmonary TB for Pulmonary hypertension as early intervention will improve chances of survival. Aim and objectives: To assess the prevalence of pulmonary hypertension in patients of active pulmonary tuberculosis and its effect on physiological impairment, radiological abnormalities and echocardiographic parameters. Material and methods: The study was conducted in the department of Medicine, Maharani Laxmi Bai Medical College, Jhansi, (UP) on the 150 patients of pulmonary tuberculosis. Ethical approval for the study was obtained from the ethical committee of the hospital and all patients gave informed consent to take part in the study. Results: In our study out of 150 patients, the majority of patients were males–105 (70%), rest were female i.e. 45 (30%). According to found data majority of patients were found in age group of 31–50 yrs i.e. 65 (43.33%) followed by age group 51–80 i.e. 64 (42.67%) and minimum patients were found in age group 10–30 yrs i.e. 21 (14%) out of 150 patients. Mean±SD of different age groups in all 150 patients 10–30 yrs, 31–50 yrs and 51–80 yrs are 26.24±4.57, 41.58±4.83 and 68.75±4.50 respectively. 7 patients are having MDR, out of these patients, 4 (7.27%) patients having pulmonary hypertension in total 55 PH patients. P–values of this relation is 0.0379, i.e. statistically significant. Patients found SpO2 < 95% i.e. 36 (64.45%) and rest were 19 (34.55%). P–value is 0.0001, i.e. statistically highly significant. Conclusion: From the observation, it appears that the “tuberculosis associated PH” as described by us is a distinct entity. Tuberculosis may have a causal association with PH and history of pulmonary tuberculosis, therefore, should be sought in all cases of PH, especially in the developing world. History of smoking apparently makes two distinct phenotypes in these patients as (a) COPD phenotype, and (b) interstitial lung disease phenotype; the later looks worse as per the PA pressure and the health status

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Article: Download PDF    DOI : 10.36106/ijsr  

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PULMONARY HYPERTENSION IN PULMONARY TUBERCULOSIS PATIENTS, Dr. Rajat Jain, Dr. Zaki Siddiqui, Dr. Sunit Kumar Verma INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-6 | June-2020

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