QUANTITATIVE EVALUATION OF SALIVARY GLAND FUNCTION IN DIFFERENTIATED THYROID CANCER PATIENTS BEFORE AND AFTER TREATMENT WITH RADIOACTIVE IODINE 131 THERAPY

Yadav Naveen; Rather Tanveer Ahmad; Khan Shoukat H

Volume : VII, Issue : III, March - 2018

QUANTITATIVE EVALUATION OF SALIVARY GLAND FUNCTION IN DIFFERENTIATED THYROID CANCER PATIENTS BEFORE AND AFTER TREATMENT WITH RADIOACTIVE IODINE 131 THERAPY

Yadav Naveen, Rather Tanveer Ahmad, Khan Shoukat H

Abstract :

Radioactive Iodine 131 is the major modality of treatment of Differentiated thyroid cancer. In the process of concentrating the RAI salivary glands are exposed to the damaging effects of iodine 131. Salivary gland scintigraphy can quantitatively evaluate the salivary gland function to see the effect of RAI therapy on salivary glands. This study was performed to quantitatively evaluate the salivary gland functions in DTC patients before and after treatment with RAI therapy.

Material and methods: 20 patients underwent the salivary gland scintigraphy using Tc 99m pertechnetate before RAI therapy and after treatment with RAI therapy at 3 months and 1 year. 12 age and sex matched controls were also taken.

Results: Patients shows significant decrease in Ejection fraction at 3 month at compared to base line and shows improvement at 1 year but do not reach the baseline.

Conclusion: After RAI therapy salivary gland functions temporarily decrease at 3 month but improved at 1 year but do not touch the baseline.

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