Radical Scavenging Activity and Invitro Anticarcinogenic Potential of Dried and Powdered Mangosteen (Garcinia mangostana) Pericarp

Divya Raichu Jacob; Nora Vigasini

Volume : V, Issue : X, October - 2016

Radical Scavenging Activity and Invitro Anticarcinogenic Potential of Dried and Powdered Mangosteen (Garcinia mangostana) Pericarp

Divya Raichu Jacob, Nora Vigasini

Abstract :

Mangosteen is an emerging category of novel functional foods that has strong antioxidant strength that has the ability to reduce diseases. The pericarp of mangosteen, which is regarded as a waste product is rich in antioxidants. The volatile bioactive compounds in the pericarp were identified using Gas Chromatography–Mass Spectrometry(GC–MS). Certain phytochemicals having antioxidant and anticarcinogenic effects in the pericarp of mangosteen were identified and quantified. The antioxidant potential of methanolic extract of dried and powdered mangosteen pericarp was determined by DPPH (1,1 diphenyl– 2–picryl hydrazyl) assay. It was found that the ability of mangosteen pericarp to scavenge DPPH radical, a stable free radical was comparable to that of Vitamin C, which is a potent antioxidant. The damage to cells caused by free radicals, especially to DNA play an important role in the development of cancers and other health conditions. The antioxidants in the pericarp of mangosteen have the potential to prevent free radical damage