IJSR - International Journal of Scientific Research

Dr.  Manish Loyal; Dr. Sunil Chauhan; Dr. Mamta Khandelwal

Volume : VI, Issue : I, January - 2017

RANDOMIZED DOUBLE BLIND COMPARATIVE STUDY OF INTRAVENOUS CLONIDINE AND TRAMADOL IN POST SPINAL ANAESTHESIA SHIVERING

Dr. Manish Loyal, Dr. Sunil Chauhan, Dr. Mamta Khandelwal

Abstract :

BACKGROUND & OBJECTIVES:Control of post spinal shivering is essential for optimal peri–operative care as shivering is a cause of discomfort and dissatisfaction in patients undergoing operations under spinal anaesthesia. The aim of the study is to assess the efficacy and safety of intravenous Clonidine and Tramadol in the treatment of post spinal intra–operative shivering.

MATERIALS AND METHODS: In this prospective, double blind, randomized study, 80 ASA grade I and II patients of patients aged 20 –60 years, scheduled for various elective surgical procedures under spinal anaesthesia with hyperbaric Bupivacaine and who developed shivering grade 3 or 4 were selected. The patients were divided into three groups of 40 each. Group– C (n=40) comprised of the patients who received Clonidine 30mcg intravenously, and Group T (n=40) receiving Tramadol 50mg IV. The efficacy and response rate of the study drugs were evaluated and recorded. Side effects like, nausea, vomiting, dizziness, hypotension, adycardia, and sedation if present, were recorded.

RESULTS: Tramadol group shows complete control of post spinal shivering with none or lesser and mild degree of side effects..The mean interval between the injection of drug (tramadol and clonidine) and the complete cessation of shivering was 2.77 and 5.47 minutes, respectively (P=.0059). Response rate is 95% in Group T and 82.5% IN Group C. CONCLUSION: We can derive at a conclusion that Tramadol in dose of 50mg is more effective than clonidine (30mcg), in treating post spinal anaesthesia shivering due to its rapid onset, effective control and minimum side effects.