IJSR - International Journal of Scientific Research

Dr. Prashant Gokul Tiple; Dr. Deoraj Sinha

Volume : VII, Issue : XI, November - 2018

Recurrence of schizophrenia in Antipsychotic drug defaulter patients of rural hospital of Jawaharlal Nehru Medical College, Sawangi, Meghe, Wardha.

Dr. Prashant Gokul Tiple, Dr. Deoraj Sinha

Abstract :

Background – In India many schizophrenic patients do not complete the course of

Anti psychotic medications and discontinue it due to poor financial condition

which results in early recurrence of schizophrenia.

Aims – 1. To know factors influencing ‘Time Interval’ between discontinuation of

Antipsychotic drugs and recurrence of Schizophrenia.

Method – A total of sixty (n=60) schizophrenic patients having active signs and symptoms were cross sectionally studied from First October 2007 to July 2008 in terms of dose , duration of Antipsychotic drugs, equivalent to Chorpromazine received in last episode. For assessment of Positive and Negative symptoms of Schizophrenia the Positive and Negative Syndrome Scale (PANSS ) was applied.

Result. – One day of Antipsychotic medication provides protection from recurrence of schizophrenia for 0.4417 day and 637.91 mg Chlorpromazine equivalent of Antipsychotic medications per day provides protection for 0.3715 days.

Conclusions – As the schizophrenia is not curable but highly treatable disease, long term

Pharmacotherapy and consultation with psychiatrist is mandatory .