Volume : IX, Issue : III, March - 2020

Reversible renal failure in 88 year old female –PPI The Culprit

Sonam R, Mulimani Mallanna, Ambali P Anand

Abstract :

Granulomatous interstitial nephritis (GIN) is rare entity detected in 0.5–0.9 % of renal biopsies and a proton‑pump inhibitor‑induced GIN is infrequent. Our patient, a 80‑year‑old female (2019), on antihypertensive with normal renal function, after 30 days of rabeprazole presented with raised serum creatinine (6.5mg/dl), biopsy revealed GIN, workup for secondary causes were negative, on detailed inquiry, the patient was receiving rabeprazole for the last 1 month on the prescription of her primary physician for dyspeptic symptoms. On stopping rabeprazole, serum creatinine reduced to baseline (1 mg/dl) at 15 days, confirming the diagnosis of rabeprazole‑induced GIN.

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Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

REVERSIBLE RENAL FAILURE IN 88 YEAR OLD FEMALE -PPI THE CULPRIT, Sonam R, Mulimani Mallanna, Ambali P Anand INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-3 | March-2020

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