Volume : VI, Issue : VIII, August - 2017
ROBINSON CYTOLOGICAL GRADING OF BREAST CARCINOMA AND ITS COMPARISON WITH ELSTON’S MODIFICATION OF BLOOMRICHARDSON HISTOPATHOLOGICAL GRADING
Dr Jigna Patel, Dr Rutik Thorat
Abstract :
Objectives
Breast carcinoma is the second most common malignancy in women. It is a malignant with heterogeneous prognosis. Because of the enhanced effects of new chemotherapeutic agents on the survival of patients with east cancer, there has been an increased interest in the use of prognostic factors like Lymph node status, tumor size, nuclear grade, steroid receptor content, tumor type and cellular proliferation rate. The cytological grading system introduce by Robinson et al. corresponds to the histologic grading method of Elston’s modification of Scarff Bloon Richardson. The present study was undertaken to correlate the cyto–histological grading of invasive east carcinomas and to assess the importance of grading.
Methods
The present study was conducted on a sample size of 62 patients for over a span of 26 months. 62 Patients who underwent FNAC and mastectomy for east carcinoma were cytologically and Histologically Graded. The results obtained by both grading methods were then compared.
Results
In the present study, the age of the subjects ranged fromless than 40 to above 60 years. All were female. On comparison of the cytological and histological grades, 93% cases were grade III, 91% cases were grade II, 55% were grade I both on cytology and histology. Cytological grading of tumor show strong agreement with histologic grading of tumors.(weighted kappa – 0.821)
Conclusion
The present study proves that, a simple cytological grading helps in evaluating the prognosis of the patient and provides varied treatment options depending on the grade.
Keywords :
Breast cancer cyto–histological correlation Scarff fBloon Richardson Histopathological Grading Robinson Cytological Grading
Article:
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DOI : 10.36106/ijsr
Cite This Article:
Dr Jigna Patel, Dr Rutik Thorat, ROBINSON CYTOLOGICAL GRADING OF BREAST CARCINOMA AND ITS COMPARISON WITH ELSTON¥S MODIFICATION OF BLOOMRICHARDSON HISTOPATHOLOGICAL GRADING, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-8 | AUGUST‾2017
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References :
Dr Jigna Patel, Dr Rutik Thorat, ROBINSON CYTOLOGICAL GRADING OF BREAST CARCINOMA AND ITS COMPARISON WITH ELSTON¥S MODIFICATION OF BLOOMRICHARDSON HISTOPATHOLOGICAL GRADING, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-8 | AUGUST‾2017
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