Volume : V, Issue : IV, April - 2016

ROLE OF ALBUMIN IN ESTIMATION OF HBA1c IN SOUTH INDIAN SUBJECTS

Jhansi Rani C, Sarojini C, Vijaya Chandra Mouli M

Abstract :

 Background: Diabetes is a common endocrine disorder characterized by hyperglycemia leading to non enzymatic glycation of free amino groups of protein (of lysine residues) and leads to their structural and functional changes resulting in complication of diabetes. Albumin which is extensively glycated in diabetes its level could regulate plasma hemoglobin glycation. Aim: The present study aimed to evaluate the relation between Sr albumin and glycohemoglobin. Material and Methods: A total of fifty subjects aged >35 years were included in the study. All the study groups including control groups were attending Chalmeda Anand Rao Institute of Medical Sciences (CAIMS) Hospital, Karimnagar, Telangana State, India. Results: There was a significant negative correlation between HBA1C and Serum albumin concentration. The mean and S.D. of fasting blood sugar of Group I subjects 83± 17.6, where mean and SD of Sr. albumin and HBA1C of Group I subjects 4.29± 0.41 and 5.7± 1.45 respectively. In Group II subject fasting plasma glucose 125.68± 23.97 where concentrations of Sr albumin and HBA1C are 3.29±0.41 and 7.73±0.8 respectively. Where the p value < 0.00. Conclusion: Serum albumin negatively correlates with HBA1C. So, an average glucose levels from the HBA1C concentration, which may efficiently inform patients their glycemic control needs to be further investigated.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Jhansi Rani C, Sarojini C, Vijaya Chandra Mouli M ROLE OF ALBUMIN IN ESTIMATION OF HBA1c IN SOUTH INDIAN SUBJECTS International Journal of Scientific Research, Vol : 5, Issue : 4 APRIL 2016

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