Volume : VIII, Issue : IX, September - 2019

Role of Cancer antigen 125(CA 125) in ovarian carcinoma patients.

Dr. Manisha, Dr Ruchi Jindal, Dr. K. L. Mali

Abstract :

Background: The term "ovarian cancer" includes several different types of cancer that arise from cells of the ovary, most commonly, tumors arise from the epithelium or lining cells of the ovary . CA–125 is the most frequently used biomarker for ovarian cancer detection One of the most common and heavily researched screening tools today is elevation of the blood protein CA–125. Robert Bast (1980) first discovered the biomarker and he believes that although the CA–125 blood test is at par with mammography in terms of cost–effectiveness and potential years of life. Material & methods: The present study was conducted at GEETANJALI MEDICAL COLLEGE AND HOSPITAL, Udaipur (Rajasthan). Total 100 cases (females) attending the obstetrics and gynecology department for some gynecological and other problem were selected for this study between the age of 40–60 years, who were attending cancer centre at GEETANJALI MEDICAL COLLEGE AND HOSPITAL, Udaipur (Rajasthan). GROUP I: – It consisted of healthy females control subjects (n=50) .By routine examination and tests, we ensured that all the subjects were healthy and there were no signs and symptoms or history of ovarian tumor and diseases GROUP II: – It consisted of ovarian cancer females subjects (n=50) with a history of ovarian tumor. Results: Higher level of CA–125 are found in ovarian cancer. Conclusion: The present study we highlights the importance and role of serum CA 125 in diagnosis, prognosis and recurrence of the disease. The study shows that serum level of CA 125 was elevated (more than 35 U/ml) in 48 (96%) patients of ovarian cancer and indicates that CA 125 has high sensitivity for diagnosis of ovarian cancer.

Keywords :

Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

ROLE OF CANCER ANTIGEN 125(CA 125) IN OVARIAN CARCINOMA PATIENTS., Dr.Manisha, Dr Ruchi Jindal, Dr.K.L. Mali INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-9 | September-2019


Number of Downloads : 115


References :