ROLE OF LACTOSE NON FERMENTERS IN VENTILATOR ASSOCIATED PNEUMONIA (VAP) AND THEIR ANTIBIOGRAM

DR.PURVI GANDHI; DR. MINAL TRIVEDI; DR.MAHENDRA VEGAD

Volume : VII, Issue : XII, December - 2018

ROLE OF LACTOSE NON FERMENTERS IN VENTILATOR ASSOCIATED PNEUMONIA (VAP) AND THEIR ANTIBIOGRAM

Dr. Purvi Gandhi, Dr. Minal Trivedi, Dr. Mahendra Vegad

Abstract :

Introduction: Ventilator associated pneumonia(VAP) is the serious hospital acquired infection, occurs in intensive care units(ICU) which is associated with high mortality rate.This prospective study was done to determine causative agent and their resistant mechanism.

Aim:To study antibiogram of Lactose non fermenters and phenotypic detection of carbapenamase producers among them.

Method:Total 170 sample of endotracheal aspirates were collected from different ICU of tertiary care hospital, Gujarat .Culture of endotracheal aspirateswas done by Semi–quantitative method and Antibiotic susceptibility testing was done by Kirby Bauer method of disk diffusion. All gram– negative bacilli (GNB) were tested for MBL (Metallo–betalactamase) production by a Combination disc method.

Result: Of the 170 patients, 59 (35%) developed VAP during their ICU stay.Most common isolates were Pseudomonas followed by Acinetobacter and other gram negative bacilli and gram positive cocci.

Conclusion: Amongst the Carbapenamase producers Pseudomonas was the most common at 33.3% followed by Acinetobacter