ROLE OF SPECKLE TRACKING IN DETECTING SUBCLINICAL LEFT VENTRICLE DYSFUNCTION IN TYPE 2 DIABETES MELLITUS WITH NORMAL EJECTION FRACTION

DR. N. SWAMINATHAN; DR. JEFF REDLEENE.S; DR. TAMILSELVAN KUNJITHAM

Volume : VIII, Issue : V, May - 2019

ROLE OF SPECKLE TRACKING IN DETECTING SUBCLINICAL LEFT VENTRICLE DYSFUNCTION IN TYPE 2 DIABETES MELLITUS WITH NORMAL EJECTION FRACTION

Dr. N. Swaminathan, Dr. Jeff Redleene. S, Dr. Tamilselvan Kunjitham

Abstract :

BACKGROUND; Patients with normal left ventricular ejection fraction with type 2 diabetes mellitus are usually associated with diastolic dysfunction. Subclinical Left ventricle systolic dysfunction can be detected early by 2D speckle tracking. It is unclear whether duration of diabetes mellitus plays a role in impairment of LV systolic dysfunction. MATERIALS & METHODS A total of 100 type 2 diabetic patients with normal LV systolic function underwent 2D speckle tracking examination over a period of 6 months from august 2017 – Feuary 2018. They were divided in 2 groups a) DM patients < 5 years duration –50 b) DM patients > 5 years duration – 50 The two groups were subjected to the following diagnostic workup: Full medical history, full clinical examination, laboratory assessment, twelve lead resting ECG, Echocardiography study, Traditional Tissue Doppler imaging, Assessment of global longitudinal strain. Patients with IHD, Systolic dysfunction, CHD, Valvular, Arrhythmia, HOCM, Pericardial, major systemic disease had been excluded. RESULTS; 50 patients with DM with duration < 5 years had a mean GLS score of –19.2� –2.1 and DM with duration >5 years had a mean GLS score of –16.2� –2.7. Similarly, males with DM with duration <5 years had a mean GLS score of –19.5� –2.6 and diabetic males with duration > 5years had a mean GLS score of –16.2� –2.5. Females with DM with duration <5 years had a mean GLS score of –19.4� –2.3 and diabetic females with duration > 5years had a mean GLS score of –16.4� –2.1. Males with diabetes had a GLS score of –18.3� –2.2. and females with diabetes had a mean GLS score of –18.2� –2.4. CONCLUSION; Diabetic duration was strongly correlated with reduction of global LS. 2DSTE has the potential for detecting subclinical LV systolic dysfunction, and it might provide useful information for the risk stratification of an asymptomatic diabetic population.