Safety and clinical outcomes of long sirolimus–eluting stents in patients with coronary artery disease: Prospective, single–centre study with one–year outcomes

Dr. Manoj Kumar Rohit; Dr. Ramesh Patel

Volume : VII, Issue : IX, September - 2018

Safety and clinical outcomes of long sirolimus–eluting stents in patients with coronary artery disease: Prospective, single–centre study with one–year outcomes

Dr. Manoj Kumar Rohit, Dr. Ramesh Patel

Abstract :

Objective: In long coronary lesions, multiple stenting is associated with stent overlap, edge dissection, geographical miss and prolonged coronary intervention.In this regard,we evaluated clinical outcomes with implantation of single long sirolimus–eluting stents (SES) of lengths ≥38 mm in patients with coronary artery disease (CAD).

Methods:This was a prospective, single–centre study of 34 CAD patients with long coronary lesions, who underwent implantation of sirolimus–eluting stents of length ≥38 mm at a tertiary–care centre in India. Primary endpoints were stent thrombosis (ST), in–stent restenosis (ISR), target vessel revascularization (TVR), myocardial infarction (MI) and death, assessedone year post implantation of the stents. Angiographic success, procedural success and clinical success were also assessed.

Results:The study population comprised of33 (97%) males, 26 (76.5%) smokers and 14 (41.2%) hypertensives. Mean age was 53.4�12.3 years. Stents of mean length 44.3�3.2 mm were implanted.Over the one year follow–up, acute ST in one (2.9%) patient,clinical ISR in one(2.9%) patient,angiographic ISR in four(11.8%) patients,TVR in two (5.9%) patients and no incidents of MI or death were reported.

Conclusion:In patients with CAD, management of long coronary lesions with SES ≥38 mm demonstrated favourable outcomes.