Volume : IV, Issue : I, January - 2015

Safety Evaluation of Instantly Prepared Three Samples of Madhutailika Basti in Wistar Rats

Drsumitha L, Dr B S Prasad

Abstract :

Basti is regarded as the prime treatment modality among the five therapeutic measures in panchakarma.A huge number of Bastis are practicing in Ayurvedic hospitals with panchakarma centers. But to prepare the Basti formulation is a tedious process involving more manpower and time.Hence to overcome these difficulties, three methods of instant basti formulationhad been developed.But as these are non-classical method, safety is to be evaluated. In the present study, three groups of animals were selected and instant basti was administered.14 days of acute toxicity study was carried out as per OECD guidelines (420). All experimental animals were observed for the duration of 14 days. No mortality was found among any of the animals throughout the study.After washout period, animals were administered with yoga basti and organ histopathology of Brain, Lungs, Heart, Stomach, Spleen, Pancreas, Liver, Small intestine, Large intestine, Kidneys were carried out. No evident toxic signs in organs were observed in histopathology study. Hence the present study reveals that, instantly prepared three methods of Madhuthailika basti were safe as it doesn’t show any mortality and toxic signs.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DrSumitha L,Dr B S Prasad Safety Evaluation of Instantly Prepared Three Samples of Madhutailika Basti in Wistar Rats International Journal of Scientific Research, Vol : 4, Issue : 1 January 2015

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