SEROPREVALENCE OF HIV IN PATIENTS ATTENDING VCTC IN A TERTIARY CARE HOSPITAL AND SPECTRUM OF OPPORTUNISTIC INFECTIONS AND PROFILE OF CD4 COUNTS AMONG HIV PATIENTS AND MOLECULAR CHARACTERISATION OF HIV

Dr.Fathima bathool rani; Dr.P.Sankar M.D

Volume : IV, Issue : II, February - 2015

SEROPREVALENCE OF HIV IN PATIENTS ATTENDING VCTC IN A TERTIARY CARE HOSPITAL AND SPECTRUM OF OPPORTUNISTIC INFECTIONS AND PROFILE OF CD4 COUNTS AMONG HIV PATIENTS AND MOLECULAR CHARACTERISATION OF HIV

Dr. Fathima Bathool Rani, Dr. P. Sankar M. D

Abstract :

This study was conducted to evaluate the seroprevalence of HIV infection in Thanjavur by subjecting the serum samples to Rapid Card tests, confirm by ELISA and determine the CD4counts for reactive patients. To categorise the cases according to the presenting complaints and screen for Opportunistic Infections and do Molecular Characterisation for HIV-1. 11953 patients were screened for HIV by COMB-AIDS and reactive samples subjected to HIV Triline, HIV Trispot & ELISA. In which 346 were reactive andCD4 count estimated. Zeihl -Neelsen staining of sputum, culture of oral swabs for Candida, Toxoplasma, HSV-2screening by ELISA, Cryptococcal latex agglutination test for reactive cases and Molecular Characterisation of HIV-1 for 10 samples were done. Seroprevalence of HIV was 2.8%. Oral Candidiasis (39.02%) emerged as the most common Opportunistic Infection followed by Pulmonary Tuberculosis (28.03%), HSV -2 (14.45%) Toxoplasmosis (5.78%) and Cryptococcosis (3.41%). All 10 samples answered positive in PCR.