Seroprevalence of TORCH Infection in Patients with Bad Obstetric History in and around Aligarh, Northern India

Nazish Fatima; Hiba Sami; Nabeela; Parvez Anwar Khan; Haris Manzoor Khan

Volume : III, Issue : VII, July - 2014

Seroprevalence of TORCH Infection in Patients with Bad Obstetric History in and around Aligarh, Northern India

Nazish Fatima, Hiba Sami, Nabeela, Parvez Anwar Khan, Haris Manzoor Khan

Abstract :

Primary infection with TORCH complex [Toxoplasma, Rubella, Cytomegalovirus (CMV), and Herpes simplex virus II (HSV-II)] in pregnant women can lead to adverse outcome. A total of 303 sera samples were collected at Dept. of Microbiology, J.NM.C, Aligarh from pregnant women with bad obstetric history (BOH) and 75 pregnant women without BOH. IgM antibodies were detected by ELISA method using CALBIOTECH kits (USA). Of the 303 pregnant women with BOH, 16 (5.9%) were positive for Toxoplasma, 14(5.1%) were positive for Rubella, 7 (2.3%) were positive for CMV and 2 (0.6%) were positive for HSV.4 (1.58%) patients were positive for both Toxoplasma and Rubella and 2 (0.79%) were positive for Rubella and CMV. In the control group 1 (2%) sample each was positive for Toxoplasma and Rubella and none was positive for CMV& HSV (P<0.05). We recommend that all antenatal cases with such history should be routinely screened for these agents.