SERUM LACTATE DEHYDROGENASE: A CROSS LINK BETWEEN CHRONIC PERIODONTITIS AND TOBACCO

Dr. Nagaraj B Kalburgi; Dr. Arati C Koregol; Dr. Tivin Thomas; Dr. Shivaraj Warad; Dr. Jyoti Pattanshetti; Dr. Nitesh Kataria

Volume : VI, Issue : VI, June - 2017

SERUM LACTATE DEHYDROGENASE: A CROSS LINK BETWEEN CHRONIC PERIODONTITIS AND TOBACCO

Dr. Nagaraj B Kalburgi, Dr. Arati C Koregol, Dr. Tivin Thomas, Dr. Shivaraj Warad, Dr. Jyoti Pattanshetti, Dr. Nitesh Kataria

Abstract :

Background and objectives: Lactate dehydrogenase [LDH] is an intracellular enzyme released by inflammatory cells during tissue destruction. Present study was conducted to estimate and compare serum LDH levels among healthy patients, Chronic Periodontitis (CP) patients, smokers with chronic periodontitis and smokeless tobacco users with chronic periodontitis. Materials and methods: 120 subjects were selected and divided into 4 groups of 30 each. Serum samples collected were analyzed for LDH and Statistical analysis was obtained. Results: Statistically significant increase in serum LDH levels was found in tobacco users compared to CP and healthy patients. Smokeless tobacco users showed significantly higher LDH levels compared to smokers. Clinical parameters were positively correlated with LDH levels. Conclusions: LDH is a marker of tissue integrity, its raised levels is attributed to cell death and tissue eakdown in periodontitis.