Volume : VIII, Issue : IV, April - 2019
Short term efficacy and safety of biological therapies in rheumatological illness– A single centre study
Dr. Hema Murugesan, Dr Ganesan Rajan
Abstract :
Inflammatory rheumatic diseases, such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and Juvenile idiopathic arthritis(JIA) are treated with various conventional disease–modifying antirheumatic drugs (DMARDs). Conventional DMARDs used are methotrexate, leflunomide, azathioprine hydroxychloroquine and sulfasalazine. They are used as mono or combination therapies to reduce joint damage and preserve joint function. Biologic DMARDS, are the agents, made from living cells, approved for the treatment of inflammatory rheumatic diseases. Biologic therapies approved for use in inflammatory joint diseases are Tumour Necrosis Factor inhibitors, T–cell modulators and B–cell depletors, IL– 6 inhibitors and JAK inhibitors. All immuno–modulating therapies have potential side effects also. In this study, we present our experience with biological therapies in our institution.
Keywords :
SO–JIA–systemic onset juvenile idiopathic arthritis MTX–methotrexate HbsAg–Hepatitis B virus HIV–Human immunodeficiency virus DMARDS–Disease modifying anti rheumatic drugs BASDAI–Bath ankylosing spondylitis disease activity index ACR–American college of rheumatology
Article:
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DOI : 10.36106/ijsr
Cite This Article:
SHORT TERM EFFICACY AND SAFETY OF BIOLOGICAL THERAPIES IN RHEUMATOLOGICAL ILLNESS- A SINGLE CENTRE STUDY, Dr.Hema Murugesan, Dr Ganesan Rajan INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-4 | April-2019
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SHORT TERM EFFICACY AND SAFETY OF BIOLOGICAL THERAPIES IN RHEUMATOLOGICAL ILLNESS- A SINGLE CENTRE STUDY, Dr.Hema Murugesan, Dr Ganesan Rajan INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-4 | April-2019
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