Significance of Serum vitamin D level in Bronchial Asthma patients

Dr Salauddin; Dr Nafees A. Khan; Dr Md. Shameem; Prof Rakesh Bhargava

Volume : V, Issue : X, October - 2016

Significance of Serum vitamin D level in Bronchial Asthma patients

Dr Salauddin, Dr Nafees A. Khan, Dr Md. Shameem, Prof Rakesh Bhargava

Abstract :

Objectives: To determine serum vitamin D level in patient of Bronchial Asthma and compare it with controls. Subjects: Patients of age 21–60 years with diagnosis of Bronchial Asthma on the basis of clinical and radiological sign and symptoms with spirometric criteria (FEV1/FVC – <0.7 ,% FEV1 <80%) with significant onchodilatation. Controls were healthy subjects of age 21–60 years. 102 patients of Bronchial Asthma and 103 Controls were included in the study. Interventions: We measured total serum 25–(OH)–D by Diasorin competitive radioimmunoassay (RIA) (AID Diagnostika, GmbH, Strasburg, Germany. Design of study: Single–center cross–sectional study. Results: The mean Serum Vitamin 25–(OH)D of Bonchial Asthma patients was 22.8 � 8.2 ng/mL,Among controls it was 30.5 � 8.6 ng/ mL.( p <0.05). This analysis significantly shows that mean serum vit D levels was low in Asthma as compared with Controls and there is no significant difference of serum VitD in various group like age, sex and indoor/outdoor activity. Conclusions: Our study concludes that Hypovitaminosis D was highly prevalent among patient of onchial Asthma as compared to general population in same geographical area.