Single dose Nevirapine to the mother and baby in the prevention of perinatal transmission of HIV infection

Dr.B.K.Srikanth; Dr.Rajesh.D; Dr.Sanjay Sajjan; Dr.Ramesh.K

Volume : III, Issue : XII, December - 2014

Single dose Nevirapine to the mother and baby in the prevention of perinatal transmission of HIV infection

Dr. B. K. Srikanth, Dr. Rajesh. D, Dr. Sanjay Sajjan, Dr. Ramesh. K

Abstract :

In India, perinatal HIV transmission, even after treatment, accounts for 5.4 per cent of HIV cases. This study was conducted in the 3 hospitals attached to J.J.M medical college, Davangere to know the vertical transmission rate of infection among neonates born to HIV positive mothers after giving single dose 200 mg Nevirapine tablet to the mother during labour and 2mg/kg body weight to the baby within 72 hours of life. This intervention was done with fond hope and good intension that vertical transmission rate would come down. Further babies were advised appropriate artificial feeds to reduce further risk due to eat feeds. These neonates were followed up periodically for clinical and virologic evaluation and to know the mortality and morbidity. 11 out of 30 babies at 3 months of age were found seropositive. Contradictory to earlier report of effectiveness of Nevirapine, we found in our study that vertical transmission is significantly high.