Species distribution and antimicrobial resistance pattern of Coagulase-negative Staphylococci with special reference to inducible clindamycin resistance

Dr Priyanka Kalbhor; Dr Varsha Wanjare; Dr Sunanda Shrikhande

Volume : VIII, Issue : III, March - 2019

Species distribution and antimicrobial resistance pattern of Coagulase-negative Staphylococci with special reference to inducible clindamycin resistance

Dr Priyanka Kalbhor, Dr Varsha Wanjare, Dr Sunanda Shrikhande

Abstract :

Clindamycin is commonly used for treatment of staphylococcal infections. Routine tests fail to detect inducible clindamycin resistance (ICR) due to erm genes resulting in treatment failure, so there is need to detect this by D–test. Out of the total 360 staphylococcal isolates, it was found that 318 (88.33%) were isolates of S. aureus and 42 (11.67%) were CoNS isolates. S. epidermidis was most common species (88.10%). Among 42 CoNS isolates, 42(11.67%) isolates were MRCoNS. ICR was observed in 13 (30.95%) isolates, constitutive resistance was found in 8 (19.05%) isolates. Both patterns were higher in MRCoNS. False susceptibility tests may be obtained if staphylococci are not tested for ICR. So, D test should be used for detection of ICR