SPECTRUM OF INFECTION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Sangram Singh Patel; Bhawna; Ujjala Ghoshal; Anusha Venkatesan; Chandrim Sengupta

Volume : IV, Issue : VII, July - 2015

SPECTRUM OF INFECTION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Sangram Singh Patel, Bhawna, Ujjala Ghoshal, Anusha Venkatesan, Chandrim Sengupta

Abstract :

<p>&nbsp;Inflammatory bowel disease (IBD) is common chronic gastrointestinal disorder characterized by various forms of chronic mucosal and trans&ndash;mural inflammation of intestine. IBD comprises of two chronic diseases that produce inflammation of the intestine: ulcerative colitis and Crohn&rsquo;s disease. Development of IBD depends on the response to microbial flora which can be dived into two categories: macro pathogens (parasites, helminthes) and micro pathogens (bacteria, viruses).The study was done to determine the spectrum of infection in patients with inflammatory bowel disease.117 stool sample from IBD patients and 101 samples from healthy patients were collected. Macroscopic observation was done followed by microscopy along with culture methods, antigen detection of E. histolytica through ELISA and C. difficile toxin A and b detection by ELISA. Prevalence was high among patients between 30&ndash;39 years of age (34%). Average age for onset for the disease was 35.3 years. Overall positivity of microorganisms combining all diagnostic methods was 9 (18%).</p>