Volume : VI, Issue : V, May - 2017

STUDY OF AUTONOMIC FUNCTIONS HERT RATE VARIABILITY AND ASSOCIATED PARAMETERS IN NORMOTENSIVE, YOUNG HEALTHY OFFSPRING OF HYPERTENSIVE PARENTS AND NORMOTENSIVE PARENTS.

Dr. Bhuvanesh Champawat, Dr. Rajesh Pathak, Dr. Garima Bafna

Abstract :

 Introduction Essential hypertension is a ‘silent killer‘ and a major health challenge in all countries of the World. The purpose of study was undertaken to identify early autonomic dysfunction in individuals with parental history of essential hypertension.   Methodology Present study was conducted to determine differences in cardiovascular reactivity and recovery. Comparison was done between normotensive, young healthy offspring of hypertensive parents (40 cases) and normotensive parents (40 controls). Autonomic functions were assessed by RMS Digitized Polygraph Polyrite D Version 2.4 and analysis of signal was done in time and frequency domain measures. After recording baseline HRV (heart rate variability), subjects were asked to do isometric hand grip (IHG) test. HRV was recorded during the test and 5 minutes after completion of IHG. Comparison was done by paired and unpaired t test.   Results: Baseline HRV parameters were not different between control test group. There was increased LF/HF ratio, LFnu and decreased HFnu during IHG in test group versus control group. This is a measure of greater sympathetic activation in test group. Increased LFnu, LF/HFratio and decreased HFnu during recovery displayed reduced vagal reactivation on recovery from IHG in test group. There was no effect of IHG on Total power, LFpower,  HFpower and time domain indices i.e. SDNN, pNN50, and RMSDD.   Conclusion The study indicates the early existence of malfunctions in autonomic nervous system associated with increased risk of hypertension.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DR. BHUVANESH CHAMPAWAT, DR. RAJESH PATHAK, DR. GARIMA BAFNA, STUDY OF AUTONOMIC FUNCTIONS HERT RATE VARIABILITY AND ASSOCIATED PARAMETERS IN NORMOTENSIVE, YOUNG HEALTHY OFFSPRING OF HYPERTENSIVE PARENTS AND NORMOTENSIVE PARENTS., INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | Issue‾5 | May‾2017

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