STUDY OF BETA HCG IN CERVICOVAGINAL SECRETIONS IN WOMEN WITH PRETERM LABOUR AND NORMAL PREGNANCY

Madhulika Mishra; Richa Rathoria

Volume : VIII, Issue : III, March - 2019

STUDY OF BETA HCG IN CERVICOVAGINAL SECRETIONS IN WOMEN WITH PRETERM LABOUR AND NORMAL PREGNANCY

Madhulika Mishra, Richa Rathoria

Abstract :

Background: The aim of this prospective study was to find out association of β–hCG level in cervico–vaginal secretion with preterm labour and a cut–off value for prediction of pre–term delivery. Methods: 150 cases were enrolled between 24–36 weeks of gestation including 75 cases as control (group II) having no pre–term labour pain and 75 cases in the study group having preterm labour pain of which 50 had preterm delivery (group Ia) and 25 had term delivery(group Ib). Results: Mean value + S.D. of β–hCG (mIU/ml) in cervico–vaginal secretion in study group Ia (26.46�19.10) were significantly higher than Ib (8.34�10.62) and control group (4.62�9.69) (p<0.001). The optimum β–hCG cut off for predicting the Ia cases was > 19.16 (mIU/ml) with sensitivity 64% and specificity 92%. Conclusions: β–hCG level >19.16 mIU/ml in cervico–vaginal secretion can be used as predictor of preterm delivery in patients presenting with preterm labour.