STUDY OF CLINICAL PRESENTATION, PRECIPITATING FACTORS, SEVERITY OF DIABETIC KETOSCAIDOSIS IN TYPE 1 AND TYPE 2 DIABETICS.

Dr. S.A Kanitkar; Dr. Shweta A. Deshmukh; Dr. Anu N. Gaikwad; Dr. Rajdeb Saha; Dr. Nuvvula Siva Krishna

Volume : VIII, Issue : IV, April - 2019

STUDY OF CLINICAL PRESENTATION, PRECIPITATING FACTORS, SEVERITY OF DIABETIC KETOSCAIDOSIS IN TYPE 1 AND TYPE 2 DIABETICS.

Dr. S. A Kanitkar, Dr. Shweta A. Deshmukh, Dr. Anu N. Gaikwad, Dr. Rajdeb Saha, Dr. Nuvvula Siva Krishna

Abstract :

Background: Diabetic Ketoacidosis (DKA) is the most severe acute metabolic complication of diabetes mellitus (DM). Recent epidemiologic studies estimate that hospitalizations for DKA have increased during the past 2 decades.The present study aims to study clinical presentation, precipitating factors, severity of diabetic ketoacidosis in type1 and type2 diabetics. Methods: The present study is a cross sectional observational study including 60 patients which was completed over a period of 2 years. Patients with random Blood Glucose of >250mg%, ketonuria of 2+ or more on urine dipstick, with evidence of acidosis demonstrated by pH <7.3,HCO3−<15 mEq/L, and a high anion gap (>12) included in the study and subjected to thorough medical examination to obtain detailed history and clinical features. Results And Conclusion: Incidence of DKA declined after 4thdecad, in present study 39 (65.0%) were type 1 diabetes cases (DM1) and 21 (35.0%) were type 2 diabetics (DM2).The most common presenting symptom of DKA was abdominal pain(30%) followed by vomiting(27%) ; While infection followed by noncompliance to insulin being common precipitating factors. More severe DKA cases were among the DM1 diabetics compared to DM2 category according to the PH