STUDY OF CLINICAL PROFILE OF CONNECTIVE TISSUE DISORDERS

Dr. Hiral A. Halani; Dr. Sneha Vadhvana; Dr. Manish N. Mehta

Volume : VII, Issue : X, October - 2018

STUDY OF CLINICAL PROFILE OF CONNECTIVE TISSUE DISORDERS

Dr. Hiral A. Halani, Dr. Sneha Vadhvana, Dr. Manish N. Mehta

Abstract :

INTRODUCTION

Connective tissue disorders include inherited as well as autoimmune disorders like SLE, RA, MCTD, Scleroderma, Sjogren syndrome etc. Individuals with autoimmune diseases may have numerous antibodies which eventually lead to multiorgan involvement including musculoskeletal, cutaneous, renal, cardiopulmonary, neurological involvement. The main stays of management remains glucocorticoids and immunosuppressants.

METHODOLOGY

A one year cross sectional study was conducted in the Guru Gobind Singh Hospital, Jamnagar. 50 patients of connective tissue disorders fulfilling the inclusion criteria were included in the study.

RESULTS

In our study, the highest prevalence was noted for SLE ~ 36% followed by RA ~24. We found that the most common presentation of these disorders was constitutional and musculoskeletal features and the least common being neurological features. We also found an association between CTDS in females and adverse pregnancy outcomes.