STUDY OF CLINICAL PROFILE OF GUILLIAN BARRE’ SYNDROME WITH SPECIAL REFERENCE TO NERVE CONDUCTION STUDY

Dr. Ankita Badhiye; Dr. Sucheta Munshi; Dr. Dipti S. Shah

Volume : VI, Issue : II, February - 2017

STUDY OF CLINICAL PROFILE OF GUILLIAN BARRE’ SYNDROME WITH SPECIAL REFERENCE TO NERVE CONDUCTION STUDY

Dr. Ankita Badhiye, Dr. Sucheta Munshi, Dr. Dipti S. Shah

Abstract :

Aims and objectives: To study incidence, various clinical presentations, and patterns in electrophysiological variants of Guillian–Barre syndrome. And To compare outcome of various types of GBS.

Setting & Design: The prospective study was conducted in the Pediatric department of tertiary care hospital and medical college of western India, studied from 1^st September, 2013 till 30^th may 2016 .

Methods & Material: All clinically diagnosed cases of GUILLIAN BARRE� syndrome as per Asbury�s criteria between 1–12 years were included .EMG–NCV was done to assess the variety of GBS. In age below 3 years or a child weighing less than 12 kg was offered IVIG while in others plasma pheresis was offered .Results were analyzed.

Results: GBS constituted 0.50% of all admitted patients and 9.5% of all neurological patients.In our hospital. The mean age of presentation is 3.8 years of age in this study with the youngest being 13 months. Overall male to female sex ratio is 1.49:1 in present study which shows male preponderance. In our study, limb weakness was the most common complaint for admission found in all 137 patients which was most commonly affecting lower limbs (57.6%) followed by all four limbs in 40.22%. In present study, classical variant was most common found in 92.3% of the patients make shows ascending type of paralysis. Based on EMG NCV results, AMAN is the most common electrophysiological type of GBS reported for 54.8% followed by AIDP for 38.8%. In present study, 76 patient had received intravenous immunoglobulins (IVIG) within 72 hours of onset of symptoms which accounts for 55.5% with survival of 53 patients (70.6%).IVIG is the most commonly used modality of treatment in present study, due to younger age group were plasmapharesis was not possible. Plasmapheresis has been performed in only 27 patients (19.5%) which survival of 77.6% of the patients