Study of efficacy of Ormeloxifene in the medical management of menorrhagia

Dr Jayshree Mulik; Dr Rashmi Solanki; Dr Nilesh Agrawal

Volume : V, Issue : V, May - 2016

Study of efficacy of Ormeloxifene in the medical management of menorrhagia

Dr Jayshree Mulik, Dr Rashmi Solanki, Dr Nilesh Agrawal

Abstract :

Background: Selective Estrogen Receptive Modulators (SERM) like Ormeloxifene could be useful in DUB. Objective: To study efficacy of Ormeloxifene in medical management of menorrhagia. Methodology: 140 eligible participants were recruited for treatment with Ormeloxifene over 1.5 years in a tertiary care hospital. Observations: Haemoglobin levels increased from pre–treatment (7.827 gm%) to post treatment (9.814 gm%); the mean increase being 1.98 gm%. Endometrial thickness decreased from 11.65mm to 7.39mm, with mean difference of 4.26mm. The median PBAC score pre–treatment was 106 (range– 168 to 70) & post–treatment was 63 (range– 84 to 36); the difference being highly significant (<0.01). Conclusion: Ormeloxifene is a highly efficacious drug for the medical management of menorrhagia.