Volume : II, Issue : VI, June - 2013

Study of Hepatitis E virus IgM and IgG Antibodies– Hospital Based Approach

Dr. Dipal K Jethwa , Dr. Mehta Krunal. D, Dr Darshan Chauhan , Dr. M. M. Vegad

Abstract :

Background: Hepatitis E is an important public-health concern as a major cause of enterically transmitted hepatitis worldwide, spread primarily by faecal contaminated drinking water and is responsible for over 50% of cases of acute viral hepatitis in endemic countries. Aims & objectives: 1.To determine incidence of hepatitis E in jaundice patients admitted to the Tertiary care hospital, Ahmedabad. 2.To assess Prevalence of Hepatitis E in various Socio-economic strata. 3.To determine various age and sex specific prevalence of Hepatitis E. Material & Methods: Total 200 blood samples of patient suspected of acute viral hepatitis were collected and tested for anti HEV IgM and IgG antibody by ELISA method. Observation and Result: Out of 200 patients, 49 patients (39%) showed anti HEV IgM antibodies, while 52 patients (41%) were positive for IgG antibodies.25 patients (20%) were positive for both IgM and IgG antibodies. The anti HEV IgM antibodies were more in the 16-30 years (57.20%).while anti HEV IgG antibodies were present in equal number (38.5%) in the 16-30 and 31-45 years. Hepatitis E virus IgG and IgM antibodies positivity rate was more common in Males compare to females. Conclusion: 1.Incidence of HEV infection is maximum in young adults (15-30 years) 42% than in paediatric and old age groups. 2.Males (62%) are more seen to be infected with HEV than females (38%).

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr. Dipal K Jethwa , Dr. Mehta Krunal. D, Dr Darshan chauhan , Dr. M. M. Vegad Study of Hepatitis E virus IgM and IgG Antibodies- Hospital Based Approach International Journal of Scientific Research, Vol : 2, Issue : 6 June 2013

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