STUDY OF HOMOCYSTEINE, HIGH SENSITIVE TROPONIN–I AND CK–MB IN MYOCARDIAL INFARCTION.

JAYAKRISHNAN.S.; JAYANTHI BAI.N; SANTHIYA.G.A

Volume : IV, Issue : IX, September - 2015

STUDY OF HOMOCYSTEINE, HIGH SENSITIVE TROPONIN–I AND CK–MB IN MYOCARDIAL INFARCTION.

Jayakrishnan. S. , Jayanthi Bai. N, Santhiya. G. A

Abstract :

<p>&lt;p&gt;Myocardial infarction (MI) is a major consequence of coronary artery disease .Apart from the traditional risk factors , other novel risk factors are also found to play a major role in the progression of myocardial infarction. Of the novel risk factors, hyperhomocysteinuria is the most important culprit in the development of MI. Homocysteine is an independent and graded risk factor for vascular thrombosis .It is involved in the progression of atherosclerosis, stroke, and peripheral thrombosis. Hyperhomocysteinuria is a treatable hereditary disorder and if detected sufficiently early can modify or delay the onset of vascular diseases .In the present study cardio biomarkers, high sensitive troponin I, CK&amp;ndash;MB, and homocysteine levels are measured in MI patients and compared with healthy controls .As expected, high sensitive troponin I and CK&amp;ndash;MB are elevated in male and female MI patients. Homocysteine is definitely an independent risk factor and it is found to be elevated in 80%of male and 50% of female MI patients. Hence assessing its levels at an early stage and controlling the levels, could prevent or reduce the onset of MI in hyperhomocysteinemia. Hence it is the often neglected risk factor which is the culprit not only for MI but also for stroke, peripheral sclerosis and other types of thrombosis.&lt;/p&gt;</p>