Study of intraoperative frozen section in the diagnosis of ovarian tumors: A tertiary oncology center experience.

Dr. Hetal Patel; Dr. Biren Parikh; Dr. Siddharth Thummar

Volume : VIII, Issue : XI, November - 2019

Study of intraoperative frozen section in the diagnosis of ovarian tumors: A tertiary oncology center experience.

Dr. Hetal Patel, Dr. Biren Parikh, Dr. Siddharth Thummar

Abstract :

Introduction: Ovarian neoplasm represents the sixth most commonly diagnosed cancer among women in the world and causes more deaths per year than other causes of the female reproductive system. Objectives: Accuracy of intraoperative frozen section in comparison with histopathology in the diagnosis of the ovarian neoplasm to decide the extent of surgery. Materials and method: Hospital–based retrospective study was done on 178 patients admitted to the department of Gynecology and Obstetrics. The Gujarat Cancer & Research Institute, Ahmedabad, they were clinically and radiologically diagnosed to have ovarian neoplasm from October 2016 to October 2017. Results: Intraoperative frozen section diagnosis of all 178 ovarian specimens revealed 103 (57.3%) benign tumors, 16 (8.9%) borderline tumor, 59 (33.1%) malignant tumors. The final paraffin section diagnosis revealed 57% benign tumors, 7.8% borderline tumors, 34.8% were malignant tumors. The overall accuracy of frozen section analyses is 90%. The sensitivity and specificity for benign, borderline and malignant tumors are 100%, 92.8%, 95.1% and 98.6%, 98.1%, 100% respectively. Conclusion: Intraoperative frozen section diagnosis appears to be an accurate technique for the histopathologic diagnosis of ovarian tumors. The can be used to guide the type and extent of Surgery, especially with experienced Pathologists. However, limitations in the use of the frozen section must be recognized such as large specimens, especially mucinous subtype. Regular re–evaluation & consultation concerning disagreements between frozen section diagnosis and final permanent paraffin diagnosis should be conducted by both surgeons and pathologists as part of quality assurance to determine the most appropriate intraoperative management for a patient with ovarian tumors.