Study of Mean Blood Flow Velocities in different cerebral vessels using Transcranial Doppler Ultrasonography in children with Sickle Cell Disease

Dr Sharjaphuljhele; Dr Satyendraphuljhele; Dr Virendra K. Kurrey; Dr SBS Netam; Dr Gagan Giri Goswami

Volume : IV, Issue : VIII, August - 2015

Study of Mean Blood Flow Velocities in different cerebral vessels using Transcranial Doppler Ultrasonography in children with Sickle Cell Disease

Dr Sharjaphuljhele, Dr Satyendraphuljhele, Dr Virendra K. Kurrey, Dr Sbs Netam, Dr Gagan Giri Goswami

Abstract :

Introduction : The prevalence of SCD in the population of Chhattisgarh state is about 10 to 15% of which about 1 to 1.27% are likely to be sufferers and the rest carriers. Prevalence is more in certain communities of Chhattisgarh like Sahu, Kurmi, Nayak, Patel and some tribal populations. Stroke is a serious complication of sickle cell disease and can be predicted by using transcranial Doppler. Material and methods : This prospective cross sectional observational study, all children were undergone transcranial Doppler examinations following the criteria of the STOP (Stroke Prevention Trial in Sickle Cell Anemia) study. The time–averaged maximum mean velocities (TAMV) were determined in various cranial arteries. After data collecting, the statistically analyse. Conclusion : SCD SS children had higher mean velocity than controls and the difference was statistically significant. Mean velocity of intracranial arteries didn�t show significant changes with age