IJSR - International Journal of Scientific Research

Gajbhiye Swati B.; Bhakre Jayshree B.; Damle Ajit S.

Volume : VI, Issue : XII, December - 2017

STUDY OF METALLOBETALACTAMASE PRODUCING PSEUDOMONAS AERUGINOSA IN A TERTIARY CARE HOSPITAL FROM WESTERN INDIA

Gajbhiye Swati B. , Bhakre Jayshree B. , Damle Ajit S.

Abstract :

Introduction : Pseudomonas aeruginosa is one of the most common pathogen causing nosocomial infections. Emergence of Metallo–betalactamase producing P.aeruginosa (MBL –PA) in hospital is alarming and poses not only a therapeutic problem, but also a serious concern for infection control management. Hence the present study was conducted to find out the prevalence of MBL–PA isolated from clinical specimens in a tertiary care hospital from Weastern Maharashtra.

Material and methods : A total of 48 strains of P. aeruginosa were recovered from various clinical specimens and screened for imipenem resistance by Kirby Bauer disk diffusion method and imipenem–EDTA combined disk test according to CLSI guidelines.

Results : We found 18.75% MBL–PA ; with highest incidence in surgery, burns unit and ICU specially in high risk patients.

Conclusion : We found high prevalence of MBL–PA which appears to be worrisome. Rapid detection of MBL producing isolates is necessary to modify therapy and to initiate effective infection control to prevent their dissemination.