Study Of Pattern Of Hemoglobinopathies And Thalassemia In The Barak Valley Region Of North East India.

Dr. Rajib Biswas; Dr. Angela Phukan; Dr. Momota Naiding

Volume : VIII, Issue : IV, April - 2019

Study Of Pattern Of Hemoglobinopathies And Thalassemia In The Barak Valley Region Of North East India.

Dr. Rajib Biswas, Dr. Angela Phukan, Dr. Momota Naiding

Abstract :

Background: Identification of inherited abnormalities of hemoglobin synthesis is immensely important epidemiologically. Data pertaining to the pattern of hemoglobinopathies and thalassemias is scarce in this part of India, and hence this study. Objectives: To analyze the different Hb variants in the population of Barak Valley and adjacent areas and study their clinicohematological profile. Materials & Methods: The study was done by Sebia Capillary electrophoresis machine. Cases were referred either after getting abnormal hemogram or for premarital counseling. Results: Out of 1074 cases 63.78% (685 cases) had normal and remaining 36.2% (389 cases) had abnormal Hb pattern on electrophoresis. The male female ratio was 1.3. HbE trait (11.3%) was the commonest abnormality encountered followed by beta thalassemia trait (9.3%) among the hemoglobinpathies. Conclusion: Abnormal hemoglobins such as HbE and beta thalassemia are common among the populations of Barak Valley and its adjacent areas.