Volume : VII, Issue : V, May - 2018

STUDY OF SERUM FERRITIN IN METABOLIC SYNDROME

Dr. Haridas B. Prasad, Dr. Mohammad Irfan

Abstract :

 The metabolic syndrome consists of a constellation of metabolic abnormalities that confers increased risk of cardiovascular disease (CVD) and

Diabetes mellitus (2). In cross–sectional studies, elevated ferritin levels have been associated with hypertension, dyslipidaemia, elevated fasting
insulin and blood glucose and central adiposity (3). Elevated serum ferritin levels independently predicted incident of type 2 diabetes in
prospective studies Serum ferritin may also be an independent determinant of poor metabolic control in the diabetic patient. Hence this study was
taken up to see correlation of ferritin to metabolic syndrome and to evaluate the relationship between serum Ferritin & components of metabolic
syndrome
MATERIALS AND METHODS: 100 patients of metabolic syndrome diagnosed as per National Cholesterol Education Program Adult
Treatment Panel III (2001). – BMI, Waist hip ratio, waist circumference and BP were measured. Afer general and systemic examination Fasting
Blood sugar, Post prandial sugar, Blood urea and serum creatinine, Fasting Lipid Profile, Baseline ECG, C–reactive protein, Urine
routine/microscopy, Complete blood counts with peripheral blood smear,Fasting serum ferritin levels (immunoradiometric assay)
OBSERVATIONS –There were 62 males & 38 females with mean Age distribution of 58.02 ± 8.15year. Majority of patients (40%) were in their
sixth decade of life. Mean BMI in our study was 29.50 (±1.837), 87 (87%) of patients had blood pressure recording of more than 135/85mmhg.
Sixty six patients (66%) patients were known hypertensives on treatment., seventy five patients (75%) were known diabetics on treatment, 25
(25%) patients did not have history of diabetes.
46(46%) patients had abnormal total cholesterol (>200mg/dl), 72(72%) patients had abnormal triglycerides (>150mg/dl), 80(80%) patients had
abnormal HDL (<40mg/dl in males, <50 in females). There were 35 (35%) patients with 3 components of metabolic syndrome, 37 (37%) with 4
components and 28 (28%) with 5 components of metabolic syndrome. Central obesity was increasing significantly with increasing number of
components of metabolic syndrome p<0.05. dyslipidemia (TG) was increasing significantly with increasing number of components of metabolic
syndrome p<0.05. Serum ferritin was increasing significantly with increasing number of components of metabolic syndrome with p=0.05. It also
showed that individual components of metabolic syndrome had significant correlation with increasing number of components of metabolic
syndrome
CONCLUSION –There is a positive association between elevated iron stores, measured by serum ferritin levels, and the prevalence of the
metabolic syndrome.
2. Serum ferritin levels proportionally correlated with increasing number of components of the metabolic syndrome

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.Haridas B.Prasad, Dr. Mohammad Irfan, STUDY OF SERUM FERRITIN IN METABOLIC SYNDROME, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-5 | May-2018


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