Volume : II, Issue : III, March - 2013

Study of some new Substituted Pyrazole – Pyrimidine Derivatives as potential Anti Fungal Agents

S. Alauddin, A. Fatima

Abstract :

A number of 1–aroyl/aryloxyaceto–4–aryl–5–cyano–3–methyl pyrazolo[4,5–e]–pyridin–6–ones (3) 1–aroyl/ aryloxyaceto–4–aryl–3–methyl pyrazolo[4,5–e]–pyrido[1,2–a]–pyrimidines (4) have been prepared by Michael addition between α, β –unsaturated ketone (2) and ethyl cyanoacetate / 2 –amino pyridine in presence of ammonium acetate. These compounds have been evaluated for their anti fungal activity against Pyricularia oryzae, Puccinia graminis , Alternaria solani , Pseudopernospora cubensis and Phytopthora infestans .

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

S. Alauddin, A. Fatima Study of some new Substituted Pyrazole‾Pyrimidine Derivatives as potential Anti Fungal Agents International Journal of Scientific Research, Vol.II, Issue.III March 2013

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