STUDY OF THE ROLE OF FROZEN SECTION EVALUATION IN PATIENTS WITH BREAST LESIONS

Dr.Dhananjay Prasad; Dr.Vijay Tote; Dr Brajendra Kumar

Volume : VII, Issue : XI, November - 2018

STUDY OF THE ROLE OF FROZEN SECTION EVALUATION IN PATIENTS WITH BREAST LESIONS

Dr. Dhananjay Prasad, Dr. Vijay Tote, Dr Brajendra Kumar

Abstract :

Frozen section is an invaluable intra–operative tool for evaluation of east lumps.The aim of this study was to calculate the overall accuracy, false positivity, false negativity for frozen section of east lumps,to analyze the causes of discrepancies, and compare the data with that of published literature on frozen section of east lumps.300 frozen sections comprising 286 east lumps, 10 axillary nodes and 4 lumpectomy margins received for frozen section were analyzed. Pathology reports and slides (of both frozen and paraffin sections) were reviewed. The values were calculated using paraffin slides as the gold standard.The 286 lumps received for primary diagnosis comprised 206 malignant and 80 benign lesions. The false negativity rate was 0.42%, false positive rate 0%, deferral rate 0.84%, overall accuracy rate was 99.57%. The false negative diagnosis was an error of interpretation. False negativity rate for axillary nodes was 20% and accuracy was 80%. Accuracy for margins was 100%.Frozen section has a role despite the raging popularity of aspiration cytology in the following settings: (1) Difficult cytology (2) Evaluation of lumpectomy margins. (3) Intra–operative nodal status