STUDY ON UROPATHOGENS CAUSING URINARY TRACT INFECTION IN DIABETIC PATIENTS AND THEIR SUSCEPTIBILITY PATTERN

Kalpana Devi Venkatesan; Senthil Chander; Kalavathy Victor

Volume : V, Issue : X, October - 2016

STUDY ON UROPATHOGENS CAUSING URINARY TRACT INFECTION IN DIABETIC PATIENTS AND THEIR SUSCEPTIBILITY PATTERN

Kalpana Devi Venkatesan, Senthil Chander, Kalavathy Victor

Abstract :

The incidence of diabetes mellitus is increasing markedly throughout the world and is becoming a serious public health threat particularly in developing countries. Diabetes mellitus has long been considered to be a predisposing factor for Urinary Tract Infection (UTI) and the urinary tract is the principle site of infection in diabetic patients with increased risk of complications. Therefore the aim of the current study is to determine the spectrum of uropathogens and their antimicrobial susceptibility pattern in diabetic patients with clinically suspected UTI.Urine samples were collected from 150 diabetic patients with symptoms of UTI attending the Medicine department. The specimens were processed and examined for various uropathogens using the standard microbiological procedures. Antibiotic susceptibility testing was performed and the results were analysed as per CLSI guidelines .Out of the 150 diabetic patients with symptoms of UTI , uropathogens were isolated from 85 (56.7%) patients with females(72.7%) outnumbering males(27.3%). Escherichia coli (42.7%) was the most prevalent uropathogen followed by Enterococcus species (22.9%) Most of the isolates showed moderate to high levels of resistance to one or more antimicrobials commonly used. UTI due to emergence of resistant bacterial strains increases the cost of treatment, morbidity and mortality in diabetics. Therefore regular monitoring is essential to establish reliable information about resistance pattern of urinary pathogens for optimal empirical therapy of diabetic patients with UTI.